In 718 Isoes 1 was patrikios and komes of the Opsikion: Nic. Brev. de Boor 56. 10-11, Mango 57) (Ἰσώην πατρίκιον καὶ τοῦ λεγομένου βασιλικοῦ Ὀψικίου ἡγεμόνα), Theoph. AM 6211 (Ἰσόην τὸν πατρίκιον καὶ κόμητα τοῦ Ὀψικίου). In that year he was invited to help Artemios (the former emperor Anastasios II, Anastasios 6) to regain the throne; the news leaked and he was arrested and tortured to make him confess and he was then exiled and his property confiscated: Nic. Brev. de Boor 56, Mango 57. Theophanes records only that he was one of the friends and colleagues of Anastasios 6 (along with Theoktistos 1 and Niketas 2) who were executed when the attempt was foiled (ὡς φίλους καὶ συνδρόμους αὐτοῦ): Theoph. AM 6211.

Possibly to be identified with Isoes, patrikios and komes of the theophylakton basilikon Opsikion, owner of a seal dateable to the eighth century: DOSeals III 39.30 = Zacos and Veglery 2039. Obv.: cruciform monogram of uncertain type, with τω - .. - .. - λω in the corners. Rev.: cruciform monogram of the owner's name, of which the letters η and ω alone are legible, with ρι - κομ - ου θε - ακτου - ικου ο - ιου visible in the corners. The name and titles are to be restored: Ἰσώῃ πατρικίῳ καὶ κόμητι τοῦ θεοφυλάκτου βασιλικοῦ Οψικίου. On the identification, see Lounghis, SBS 2, pp. 7ff. For two more of this man's seals, see Likhachev, Molivdovuly 206-7 (LXXII 7 and 8), from different boulloteria, and cf. Nesbitt and Oikonomides, DOSeals III, p. 66, note. See Rochow, Konstantin V, p. 219.

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