Alypios 1 was bishop of Gangra in Paphlagonia; in 681 he attended the Third Council of Constantinople (the Sixth Ecumenical Council) and was present at the last nine sessions (from ten to eighteen, from 18 March to 16 September): Riedinger, II 2. 280-823 (= Mansi XI 389-672). In the subscriptions to the statement of the faith, which condemned monotheletism, and to the Council, he is styled Ἀλύπιος ἐλάχιστος ἐπίσκοπος τῆς Γαγγρηνῶν μητροπόλεως τῆς Παφλαγόνων ἐπαρχίας: Riedinger, II 2. 782, line 9, II 2. 823, line 31, cf. II 2. 892, line 23 (= Mansi XI 644, 672,cf. 692).

In the lists of those attending each session Alypios 1 is styled Ἀλυπίου ἐπισκόπου Γαγγρῶν: Riedinger, II 2. 280, line 24, II 2. 402, line 33, etc. (= Mansi XI 389, 457, etc.). He was among the signatories to the copy of the definition of the faith sent to the bishop of Rome, Agatho 1, signing on behalf of himself and the bishops under him: Riedinger, II 2. 892, line 23 (=Mansi XI 692) (ὑπὲρ ἐμαυτοῦ καὶ τῆς ὑπ'ἐμὲ συνόδου).

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